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Liu Y, Darville T, Zheng X, Li Q. Decomposition of variation of mixed variables by a latent mixed Gaussian copula model. Biometrics. 2022 Mar 19. doi: 10.1111/biom.13660. Epub ahead of print. PMID: 35304917.

Amaral AF, McQueen BE, Bellingham-Johnstun K, Poston TB, Darville T, Nagarajan UM, Laplante C, Käser T. Host-Pathogen Interactions of Chlamydia trachomatis in Porcine Oviduct Epithelial Cells. Pathogens. 2021 Oct 1;10(10):1270. doi: 10.3390/pathogens10101270. PMID: 34684219.

Liu C, Hufnagel K, O’Connell CM, Goonetilleke N, Mokashi N, Waterboer T, Tollison TS, Peng X, Wiesenfeld HC, Hillier SL, Zheng X, Darville T. Reduced Endometrial Ascension and Enhanced Reinfection Associated With Immunoglobulin G Antibodies to Specific Chlamydia trachomatis Proteins in Women at Risk for Chlamydia. J Infect Dis. 2022 Mar 2;225(5):846-855. doi: 10.1093/infdis/jiab496. PMID: 34610131.

Darville T. Pelvic Inflammatory Disease Due to Neisseria gonorrhoeae and Chlamydia trachomatis: Immune Evasion Mechanisms and Pathogenic Disease Pathways. J Infect Dis. 2021 Aug 16;224(Supplement_2):S39-S46. doi: 10.1093/infdis/jiab031. PMID: 34396413.

Zheng X, Zhong W, O’Connell CM, Liu Y, Haggerty CL, Geisler WM, Anyalechi GE, Kirkcaldy RD, Wiesenfeld HC, Hillier SL, Steinkampf MP, Hammond KR, Fine J, Li Y, Darville T. Host Genetic Risk Factors for Chlamydia trachomatis-Related Infertility in Women. J Infect Dis. 2021 Aug 16;224(Supplement_2):S64-S71. doi: 10.1093/infdis/jiab149. PMID: 34396400.

McQueen BE, Kollipara A, Gyorke CE, Andrews CW Jr, Ezzell A, Darville T, Nagarajan UM. Reduced uterine tissue damage during Chlamydia muridarum infection in TREM-1,3 deficient mice. Infect Immun. 2021 Jun 14:IAI0007221. doi: 10.1128/IAI.00072-21. Epub ahead of print. PMID: 34125599.

de la Maza LM, Darville TL, Pal S. Chlamydia trachomatis vaccines for genital infections: where are we and how far is there to go? Expert Rev Vaccines. 2021 Apr;20(4):421-435. doi: 10.1080/14760584.2021.1899817. Epub 2021 Apr 28. PMID: 33682583.

Zhong W, Darville T, Zheng X, Fine J, Li Y. Generalized multi-SNP mediation intersection-union test. Biometrics. 2020 Dec 14. doi: 10.1111/biom.13418. Epub ahead of print. PMID: 33316078.

Gyorke CE, Kollipara A, Allen J 4th, Zhang Y, Ezzell JA, Darville T, Montgomery SA, Nagarajan UM. IL-1α Is Essential for Oviduct Pathology during Genital Chlamydial Infection in Mice. J Immunol. 2020 Dec 1;205(11):3037-3049. doi: 10.4049/jimmunol.2000600. Epub 2020 Oct 21. PMID: 33087404.

McQueen BE, Kiatthanapaiboon A, Fulcher ML, Lam M, Patton K, Powell E, Kollipara A, Madden V, Suchland RJ, Wyrick P, O’Connell CM, Reidel B, Kesimer M, Randell SH, Darville T, Nagarajan UM. A Human Fallopian Tube Epithelial Cell Culture Model to Study Host Responses to Chlamydia trachomatis Infection. Infect Immun. 2020 Aug 19;88(9):e00105-20. doi: 10.1128/IAI.00105-20. PMID: 32601108

Amaral AF, Rahman KS, Kick AR, Cortes LM, Robertson J, Kaltenboeck B, Gerdts V, O’Connell CM, Poston TB, Zheng X, Liu C, Omesi SY, Darville T, Käser T. Mucosal Vaccination with UV-Inactivated Chlamydia suis in Pre-Exposed Outbred Pigs Decreases Pathogen Load and Induces CD4 T-Cell Maturation into IFN-γ+ Effector Memory Cells. Vaccines (Basel). 2020 Jul 2;8(3):E353. doi: 10.3390/vaccines8030353. PMID: 32630694

Dong L, Kollipara A, Darville T, Zou F, Zheng X. Semi-CAM: A semi-supervised deconvolution method for bulk transcriptomic data with partial marker gene information. Sci Rep. 2020 Mar 25;10(1):5434. doi: 10.1038/s41598-020-62330-2. PMID: 32214192

Wiesenfeld HC, Meyn LA, Darville T, Macio IS, Hillier SL. A Randomized Controlled Trial of Ceftriaxone and Doxycycline, with or Without Metronidazole, for the Treatment of Acute Pelvic Inflammatory Disease. Clin Infect Dis. 2020 Feb 13. pii: ciaa101. doi: 10.1093/cid/ciaa101. PMID: 32052831

Zhong W, Dong L, Poston TB, Darville T, Spracklen CN, Wu D, Mohlke KL, Li Y, LI Q, Zheng X. Inferring Regulatory Networks From Mixed Observational Data Using Directed Acyclic Graphs. Front Genet. 2020 Feb 7;11.8. doi: 10.3389/fgene.2020.00008. PMID: 32127796

Tang W, Mao J, Li KT, Walker JS, Chou R, Fu R, Chen W, Darville T, Klausner J, Tucker JD. Pregnancy and fertility-related adverse outcomes associated with Chlamydia trachomatis infection: a global systematic review and meta-analysis. Sex Transm Infect. 2019 Dec 13. pii: sextrans-2019-053999. doi: 10.1136/sextrans-2019-053999. PMID: 31836678

Wiringa AE, Ness RB, Darville T, Beigi RH, Haggerty CL. Trichomonas vaginalis, endometritis and sequelae among women with clinically suspected pelvic inflammatory disease. Sex Transm Infect. 2019 Nov 12. pii: sextrans-2019-054079. doi: 10.1136/sextrans-2019-054079. PMID: 31719170

Poston TB, Darville T. First genital chlamydia vaccine enters in-human clinical trial. Lancet Infect Dis. 2019 Oct;19(10):1039-1040. doi: 10.1016/S1473-3099(19)30290-7. PMID: 31416691

Poston TB, Lee DE, Darville T, Zhong W, Dong L, O’Connell CM, Wiesenfeld HC, Hillier SL, Sempowski G, Zheng X. Cervical cytokines associated with Chlamydia trachomatis susceptibility and protection. J Infect Dis. 2019 Jun 19;220(2):330-339. doi: 10.1093/infdis/jiz087. PMID: 30820577

Darville T, Albritton H, Zhong W, Dong L, O’Connell CM, Poston TB, Quayle AJ, Goonetilleke N, Wiesenfeld HC, Hillier SL, Zheng X. Anti-chlamydia IgG and IgA are insufficient to prevent endometrial Chlamydia infection in women and increased anti-chlamydia IgG is associated with enhanced risk for incident infection. Am J Reprod Immunol. 2019 May;81(5):e13103 doi: 10.1111/aji.13103. PMID: 30784128

Petrina MAB, Cosentino LA, Wiesenfeld HC, Darville T, Hillier SL. Susceptibility of endometrial isolates recovered from women from clinical pelvic inflammatory disease or histological endometritis to antimicrobial agents. Anaerobe. 2019 Apr;56:61-65. doi: 10.1016/j.anaerobe.2019.02.005. PMID: 30753898

O’Connell CM, Brochu H, Girardi J, Harrell E, Jones A, Darville T, Seña AC, Peng X. Simultaneous profiling of sexually transmitted bacterial pathogens, microbiome, and concordant host response in cervical samples using whole transcriptome sequencing analysis. Microb Cell. 2019 Jan 24;6(3):177-183. doi: 10.15698/mic2019.03.672. PMID: 30854394

Rahman KS, Darville T, Wiesenfeld HC, Hillier SL, Kaltenboeck B. Mixed Chlamydia trachomatis peptide antigens provide a specific and sensitive single-well colorimetric enzyme-linked immunosorbent assay for detection of human anti-C. trachomatis antibodies. mSphere. 2018 Nov 7;3(6). pii: e00484-18. doi: 10.1128/mSphere.00484-18. PMID: 30404936

Zheng, X, O’Connell CM, Zhong W, Poston TB, Wiesenfeld HC, Hillier SL, Trent M, Gaydos C, Tseng G, Taylor BD, Darville T. Gene Expression Signatures Can Aid Diagnosis of Sexually Transmitted Infection-Induced Endometritis in Women. Front. Cell. Infect. Microbiol. 20 September 2018. doi: 10.3389/fcimb.2018.00307. PMID: 30294592

Rahman KS, Darville T, Russell AN, O’Connell CM, Wiesenfeld HC, Hillier SL, Lee DE, Kaltenboeck B. Comprehensive Molecular Serology of Human Chlamydia trachomatis Infections by Peptide Enzyme-Linked Immunosorbent Assays. mSphere. 2018 Aug 1;3(4). pii: e00253-18. doi: 10.1128/mSphere.00253-18. PMID: 30068559

Rahman KS, Darville T, Russell AN, O’Connell CM, Wiesenfeld HC, Hillier SL, Chowdhury EU, Juan YC, Kaltenboeck B. Discovery of Human-Specific Immunodominant Chlamydia trachomatis B Cell Epitopes. mSphere. 2018 Aug 1;3(4). pii: e00246-18. Doi: 10.1128/mSphere.00246-18. PMID: 30068558

Poston TB, O’Connell CM, Girardi J, Sullivan JE, Nagarajan UM, Marinov A, Scurlock AM, Darville T. T-independent IFNγ and B cells Cooperate to Prevent Mortality Associated with Disseminated Chlamydia muridarum Genital Tract Infection. Infect Immun. 2018 Apr 16. pii: IAI.00143-18. doi: 10.1128/IAI.00143-18. PMID: 29661927

Zheng X, O’Connell CM, Zhong W, Nagarajan UM, Tripathy M, Lee D, Russell AN, Wiesenfeld H, Hillier S, Darville T. Discovery of Blood Transcriptional Endotypes in Women with Pelvic Inflammatory Disease. J immunol. 2018 Apr 15;200(8):2941-2956. Doi: 10.4049/jimmunol.1701658. Epub 2018 Mar 12. PMID: 29531169

Taylor BD, Zheng X, O’Connell CM, Wiesenfeld HC, Hillier SL, Darville T. Risk factors for Mycoplasma genitalium endometritis and incident infection: a secondary data analysis of the T cell Response Against Chlamydia (TRAC) Study. Sex Transm Infect. 2018 Mar 21. pii: sextrans-2017-053376. doi: 10.1136/sextrans-2017-053376. [Epub ahead of print] PMID: 29563165

Zhong G, Brunham RC, de la Maza LM, Darville T, Deal C. National institute of allergy and infectious diseases workshop report: “Chlamydia vaccines: the way forward”. Vaccine. 2017 Oct 30. pii: S0264-410X(17)31483-4. Doi 0.1016/j.vaccine.2017.10.075. [Epub ahead of print] PMID: 29097007

Poston TB, Qu Y, Russell A, Girardi J, Nagarajan U, Darville T. A Chlamydia-specific TCR transgenic mouse demonstrates Th1 polyfunctionality with enhanced effector function. J Immunol. 2017 Oct 15;199(8):2845-2854. doi: 10.4049/jimmunol.1700914. Epub 2017 Aug 30; PMID: 28855311

Poston TB, Gottlieb SL, Darville T. Status of vaccine research and development of vaccines for Chlamydia trachomatis infection. Vaccine. 2017 Jan 19; PMID: 28111145

Taylor BD, Zheng X, Darville T, Zhong W, Konganti K, Abiodun-Ojo O, Ness RB, O’Connell CM, Haggerty CL. Whole-Exome sequencing to identify novel biological pathways associated with infertility after pelvic inflammatory disease. Sex Transm Dis. 2017 Jan;44(1):35-41; PMID: 27898568

Russell AN, Zheng X, O’Connell CM, Wiesenfeld HC, Hillier SL, Taylor BD, Picard MD, Flechtner JB, Zhong W, Frazer LC, Darville T. Identification of Chlamydia trachomatis antigens recognized by T cells from highly exposed women who limit or resist genital tract infection. J Infect Dis. 2016 Dec 15; 214(12):1884-1892. PMID: 27738051

O’Connell CM, Ferone ME. Chlamydia trachomatis Genital Infections. Microb Cell. 2016 Sep 5;3(9):390-403. doi: 10.15698/mic2016.09.525. PMID: 28357377

Poston TB, Darville T. Chlamydia trachomatis: Protective Adaptive Responses and Prospects for a Vaccine. Curr Top Microbiol Immunol. 2016 Apr 1; PMID: 27033698

Nguyen-Ha PT, Howrie D, Crowley K, Vetterly CG, McGhee W, Berry D, Ferguson E, Polischuk E, Brooks MM, Goff J, Stillwell T, Darville T, Thompson AE, Levin JE, Michaels MG, Green M. A Quality Assessment of a Collaborative Model of a Pediatric Antimicrobial Stewardship Program. Pediatrics. 2016 May;137(5). pii: e20150316. doi: 10.1542/peds.2015-0316. Epub 2016 Apr 6. PMID: 27244775

Russell AN, Zheng X, O’Connell CM, Taylor BD, Wiesenfeld H, Hillier S, Zhong W, Darville T. Analysis of factors driving incident and ascending infection and the role of serum antibody in Chlamydia trachomatis genital tract infection. J Infect Dis. 2016 Feb 15; PMID: 26347571